業績


2021

[原著論文]

Kon N, Wang HT, Kato YS, Uemoto K, Kawamoto N, Kawasaki K, Enoki R, Kurosawa G, Nakane T, Sugiyama Y, Tagashira H, Endo M, Iwasaki H, Iwamoto T* (*co-corresponding authors), Kume K, Fukada Y*. Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms. Sci Adv. 7(18):eabe8132, 2021.

Yamada H, Sakata N, Tanaka T, Tagashira H, Yoshimatsu G, Kawakami R, Wada H, Iwamoto T, Kodama S. Lymphangiogenesis and angiogenesis rescue murine ischemic hindlimb via transient receptor potential vanilloid 4. J Pharmacol Sci. 146(4):244-248, 2021.

Uchida K, Kita T* (*co-first authors), Hatta M, Itoh SG, Okumura H, Tominaga M, Yamazaki J. Involvement of pore helix in voltage-dependent inactivation of TRPM5 channel. Heliyon. 7(1):e06102, 2021.

 

2020

[原著論文]

Nagata A*, Tagashira H* (*co-first authors), Kita S, Kita T, Nakajima N, Abe K, Iwasaki A, Iwamoto T. Genetic knockout and pharmacologic inhibition of NCX1 attenuate hypoxia-induced pulmonary arterial hypertension. Biochem Biophys Res Commun. 529(3):793-798, 2020.

Shoda W, Nomura N, Ando F, Tagashira H, Iwamoto T, Ohta A, Isobe K, Mori T, Susa K, Sohara E, Rai T, Uchida S. Sodium-calcium Exchanger 1 Is the Key Molecule for Urinary Potassium Excretion Against Acute Hyperkalemia. PLoS One 15(6):e0235360, 2020.

Sulistomo HW, Nemoto T* (*co-first authors), Kage Y, Fujii H, Uchida T, Takamiya K, Sumimoto H, Kataoka H, Bito H, Takeya R. Fhod3 controls the dendritic spine morphology of specific subpopulations of pyramidal neurons in the mouse cerebral cortex. Cereb Cortex. doi: 10.1093/cercor/bhaa355, 2020.

[著書・総説]

岩本隆宏 SLC41 Mg2+輸送体の最近の話題 マグネシウム 39(1):30-36, 2020.

岩本隆宏 心不全治療薬 エース薬理学(金井好克 監修),南山堂(東京),pp135-141, 2020.

岩本隆宏 AGORA 一薬理学者の莫妄想 日薬理誌 155(4):199-200, 2020.

Nemoto T*, Tagashira H* (*co-first authors), Kita T, Shibata S, Nakajima N, Gotoh Y, Kita S, Iwamoto T. Pharmacological exercise using a computer simulation of isolated preparation of guinea-pig ileum. Med Bull Fukuoka Univ 47(1):93-99, 2020.

柳田俊彦, 丸太豊明, 根本隆行 インスリンと記憶:海馬におけるその働きと治療へのアプローチ, 臨床麻酔 533:307-316, 2020.

 

2019

[原著論文]

Moriguchi S*, Kita S, Inagaki R, Yabuki Y, Sasaki Y, Ishikawa S, Sakagami H, Iwamoto T* (*co-corresponding authors), Fukunaga K. Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice. Mol Neurobiol. 56(6):4381-4394, 2019

Maruta T*, Nemoto T* (*co-first authors), Hidaka K, Koshida T, Shirasaka T, Yanagita T, Takeya R, Tsuneyoshi I. Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain. PLoS One 14(11):e0225586, 2019

Kita T, Mino H, Ozoe F, Ozoe Y. Spatiotemporally different expression of alternatively spliced GABA receptor subunit transcripts in the housefly Musca domestica. Arch Insect Biochem Physiol 101(1):e21541, 2019

Kita T, Uchida K, Kato K, Suzuki Y, Tominaga M, Yamazaki J. FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels. J Physiol Sci. 69(2):305-316, 2019.

[著書・総説]

岩本隆宏田頭秀章喜多紗斗美 Na+/Ca2+交換輸送体の構造・機能の解明から治療への応用 医学のあゆみ 271(1):42-48, 2019.

田頭秀章, 根本隆行, 柴田志保, 喜多知, 後藤雄輔, 喜多紗斗美, 岩本隆宏 Wingnetシステムを利用したP-Drug適正薬剤選択演習, 大学ICT推進協議会 2019年度年次大会論文集, 1-3, 2019.

根本隆行, 田頭秀章, 喜多知, 柴田志保, 後藤雄輔, 喜多紗斗美, 岩本隆宏 薬物反応シミュレーションソフトを利用したアクティブ・ラーニング型医学演習, 大学ICT推進協議会 2019年度年次大会論文集, 1-3, 2019.

 

2018

[原著論文]

Moriguchi S, Kita S, Fukaya M, Osanai M, Inagaki R, Sasaki Y, Izumi H, Horie K, Takeda J, Saito T, Sakagami H, Saido TC, Iwamoto T*, Fukunaga K* (*co-corresponding authors). Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice. Neuropharmacology 131:291-303, 2018.

Bai X, Ihara E, Hirano K, Tanaka Y, Nakano K, Kita S, Iwamoto T, Ogino H, Hirano M, Oda Y, Nakamura K, Ogawa Y. Endogenous hydrogen sulfide contributes to tone generation in porcine lower esophageal sphincter via Na+/Ca2+ exchanger. Cell Mol Gastroenterol Hepatol. 5(3):209-221, 2018.

Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K. Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy. Mol Psychiatry 23(2):211-221, 2018.

Moriguchi S, Kita S, Yabuki Y, Inagaki R, Izumi H, Sasaki Y, Tagashira H, Horie K, Takeda J, Iwamoto T*, Fukunaga K* (*co-corresponding authors). Reduced CaM kinase II and CaM kinase IV activities underlie cognitive deficits in NCKX2 heterozygous mice. Mol Neurobiol. 55(5):3889-3900, 2018.

Arita S, Hatta M, Uchida K, Kita T, Okamura K, Ryu T, Murakami H, Sakagami R, Yamazaki J. Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats. J Periodontal Res. 53(5):750-761, 2018

Ishii T, Uchida K, Hata S, Hatta M, Kita T, Miyake Y, Okamura K, Tamaoki S, Ishikawa H, Yamazaki J. TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-β1 in an in vitro wound healing model of rats. J Dermatol Sci. 90(3):332-342, 2018.

[著書・総説]

Moriguchi S, Kita S, Iwamoto T, Fukunaga K. Dysfunction of Na+/Ca2+ exchangers is associated with cognitive decline in Alzheimer's disease. Nihon Yakurigaku Zasshi 152(6):299-305, 2018

田頭秀章 ミトコンドリアCa2+シグナルの心筋保護機能に関する最近の知見, ファルマシア 54(2):168, 2018.

Tagashira H*, Nagata A* (*co-first authors), Kita S, Suzuki S, Iwasaki A, Iwamoto T. Calcium signaling abnormality in pulmonary arterial hypertension. Med Bull Fukuoka Univ 45(1):45-50, 2018.

 

2017

[原著論文]

Nishiyama K, Tanioka K, Azuma YT, Hayashi S, Fujimoto Y, Yoshida N, Kita S, Suzuki S, Nakajima H, Iwamoto T, Takeuchi T. Na+/Ca2+ exchanger contributes to stool transport in mice with experimental diarrhea. J Vet Med Sci. 79(2):403-411, 2017.

Yamamoto S, Muramatsu M, Azuma E, Ikutani M, Nagai Y, Sagara H, Koo BN, Kita S, O'Donnell E, Osawa T, Takahashi H, Takano KI, Dohmoto M, Sugimori M, Usui I, Watanabe Y, Hatakeyama N, Iwamoto T, Komuro I, Takatsu K, Tobe K, Niida S, Matsuda N, Shibuya M, Sasahara M. A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS. Sci Rep. 7(1):3855, 2017.

Tashiro M, Watanabe Y, Yamakawa T, Yamashita K, Kita S, Iwamoto T, Kimura J. Suppressive Effect of carvedilol on Na+/Ca2+ exchange current in isolated guinea-pig cardiac ventricular myocytes. Pharmacology 99(1-2):40-47, 2017.

Hirota K, Hirata K, Shibata S, Shigematsu K, Higa K, Yamaura K. Risk vessels of retropharyngeal hematoma during stellate ganglion block. Reg Anesth Pain Med. 42(6):778-781, 2017.

 

2016

[原著論文]

Fujimoto Y, Hayashi S, Azuma YT, Mukai K, Nishiyama K, Kita S, Morioka A, Nakajima H, Iwamoto T, Takeuchi T. Overexpression of Na+/Ca2+ exchanger 1 display enhanced relaxation in the gastric fundus. J Pharmacol Sci. 132(3):181-186, 2016.

Yamashita K, Watanabe Y, Kita S, Iwamoto T, Kimura J. Inhibitory effect of YM-244769, a novel Na+/Ca2+ exchanger inhibitor on Na+/Ca2+ exchange current in guinea pig cardiac ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 389(11):1205-1214, 2016.

Nishiyama K, Azuma YT, Morioka A, Yoshida N, Teramoto M, Tanioka K, Kita S, Hayashi S, Nakajima H, Iwamoto T, Takeuchi T. Roles of Na+/Ca2+ exchanger isoforms NCX1 and NCX2 in motility in mouse ileum. Naunyn Schmiedebergs Arch Pharmacol. 389(10):1081-1090, 2016.

Azuma YT, Hayashi S, Nishiyama K, Kita S, Mukai K, Nakajima H, Iwamoto T, Takeuchi T. Na+/Ca2+ exchanger-heterozygote knockout mice display increased relaxation in gastric fundus and accelerated gastric transit in vivo. Neurogastroenterol Motil. 28(6):827-836, 2016.

Wei J, Watanabe Y, Takeuchi K, Yamashita K, Tashiro M, Kita S, Iwamoto T, Watanabe H, Kimura J. Nicorandil stimulates a Na+/Ca2+ exchanger by activating guanylate cyclase in guinea pig cardiac myocytes. Pflugers Arch. 468(4):693-703, 2016.

Shinoda Y*, Tagashira H* (*co-first authors), Bhuiyan MS, Hasegawa H, Kanai H, Zhang C, Han F, Fukunaga K. Corticosteroids mediate heart failure-induced depression through reduced σ1-receptor expression. PLoS One 11(10):e0163992, 2016.

Shinoda Y*, Tagashira H* (*co-first authors), Bhuiyan MS, Hasegawa H, Kanai H, Fukunaga K. Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction. J Pharmacol Sci. 131(3):172-183, 2016.

[著書・総説]

喜多紗斗美, 岩本隆宏 利尿薬,イラストレイテッド薬理学 (柳澤輝行,他編),丸善(東京),pp265-280, 2016.

 

2015

[原著論文]

Wang Y, Chen L ,Li M, Cha H, Iwamoto T, Zhang J. Conditional knockout of smooth muscle sodium calcium exchanger type-1 lowers blood pressure and attenuates AngiotensinⅡ-salt hypertention. Physiol Rep. 3(1): e12273, 2015.

Gotoh Y*, Kita S*(*co-first authors), Fujii M, Tagashira H, Horie I, Arai Y, Uchida S, Iwamoto T. Genetic knockout and pharmacologic inhibition of NCX2 cause natriuresis and hypercalciuria. Biochem Biophys Res Commun.456(2):670-675, 2015.

[著書・総説]

岩本隆宏 薬物標的となるイオントランスポーター 図解薬理学 (編集:鍋島俊隆・井上和秀) 48-54, 2015.

Kita S, Tagashira H, Gotoh Y, Fujii M, Iwamoto T. Phosphoinositide analysis using the HPLC system equipped with a fraction collector and the TSKgel SAX column. Med. Bull. Fukuoka Univ. 42(1): 175-181, 2015.

安西尚彦、岩本隆宏 創薬応用を目指すチャネル・トランスポーター研究最前線 臨床薬理 46(1): 29, 2015.

岩本隆宏 Na+/Ca2+交換体と循環器系疾患:創薬標的としての可能性 臨床薬理 46(1): 30-32, 2015.

後藤雄輔、柳田俊彦、喜多紗斗美田頭秀章岩本隆宏 医学部薬理学教育におけるロールプレイ演習の導入 福大医学紀要 42(1): 183-188, 2015.

岩本隆宏、西田基宏 心血管膜輸送分子の構造・病態の統合的研究戦略 生理学研究所年報 第36巻 362-380, 2015.

岩本隆宏喜多紗斗美後藤雄輔田頭秀章 薬理学テキスト(第6版) 1-344, 2015. 櫂歌書房

 

2014

[原著論文]

Nishiyama K, Morioka A ,Kita S, Nakajima H, Iwamoto T, Azuma YT, Takeuchi T. Na+/Ca2+ exchanger 1 transgenic mice display increased relaxation in the distal colon. Pharmacology. 94(5-6):230-238,2014.

Sakai Y,Hashimoto M, Enkhjargal B, Mitsuishi H, Nobe H, Horie I, Iwamoto T. Yanagimoto K. Effects of Krill-derived phospholipid-enriched n-3 fatty acids on Ca2+regulation system in cerebral arteries from ovariectomized rats. Life Sci. 100(1):18-24, 2014.

Tagashira H, Bhuiyan MS, Shioda N, Fukunaga K. Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ1-receptor in hypertrophic cardiomyocytes. Life Sci. 95(2): 89-100, 2014.

Tagashira H, Shinoda Y, Shioda N, Fukunaga K. Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis. Biochim Biophys Acta. 1840(12): 3320-3334, 2014.

[著書・総説]

岩本隆宏、久保義弘 心血管膜輸送分子の構造・機能・病態の統合的研究戦略 生理学研究所年報 第35巻 261-271, 2014.

岩本隆宏喜多紗斗美藤井誠後藤雄輔田頭秀章 薬理学テキスト(第5版) 1-345, 2014. 櫂歌書房

 

2013

[原著論文]

Nishizawa T, Kita S, Maturana AD, Furuya N, Hirata K, Kasuya G, Ogasawara S, Dohmae N, Iwamoto T, Ishitani R, Nureki O. Structural basis for counter-transport mechanism of H+/Ca2+ exchanger. Science.341(6142): 168-172, 2013.

MeraT, Itoh T, Kita S(co-first authors), Kodama S, Kojima D, Nishinakamura H, Okamoto K, Ohkura M, Nakai J, Iyoda T, Iwamoto T, Matsuda T, Baba A, Omori K, Ono J, Watarai H, Taniguchi M, Yasunami Y. Pretreatment of donorislets with the Na+/Ca2+ exchanger inhibitor improves the efficiency of islet transplantation. Am J Transplant.13(8): 2154-2160, 2013.

Yamamura H, Cole WC, Kita S, Hotta S, Murata H, Suzuki Y, Ohya S, Iwamoto T, Imaizumi Y. Overactive bladder mediated by accelerated Ca2+ influx mode of Na+/Ca2+ exchanger in smooth muscle. Am J Physiol Cell Physiol. 305(3): C299-C308, 2013.

Nishiyama K, Azuma YT, Kita S, Azuma N, Hayashi S, Nakajima H, Iwamoto T, Tkeuchi T. Na+/Ca2+ exchanger 1/2 double-heterozygote knockout mice display increased nitric oxide component and altered colonic motility. J Pharmacol Sci. 123(3): 235-245, 2013.

Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S. Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin Ⅱ. Hypertension. 62(5a): 872-878, 2013.

Fujii M†, Kawai K†(†co-first authors), Egami Y, Araki N, Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation. Scientific Rep. 3(Article number 2385), 1-10, 2013

[著書・総説]

喜多紗斗美藤井誠岩本隆宏 Ca2+トランスポーターと循環器疾患 医学のあゆみ 245(1): 51-56, 2013.

喜多紗斗美後藤雄輔堀江一郎藤井誠山下知宏岩本隆宏  医学部薬理学教育におけるP-Drug実習の導入 福大医学紀要 40(1/2): 81-85, 2013.

岩本隆宏喜多紗斗美 真核生物 CaCA結晶構造から哺乳類NCXの変異解析を検証する 日薬理誌 142(6): 318-319, 2013.

藤井誠喜多紗斗美、平田雅人、岩本隆宏 脂質シグナル研究のためのHPLC分析技術:イノシトールリン脂質/イノシトールポリリン酸の分離と定量 日薬理誌 142(5): 236-240, 2013.

Fujii M, Kita S, Gotoh Y, Horie I, Iwamoto T. Quantitative analysis and cell distribution imaging of phosphoinositides. Med Bull Fukuoka Univ. 40(3/4): 209-217, 2013.

岩本隆宏喜多紗斗美藤井誠堀江一郎後藤雄輔 薬理学テキスト(第4版) 1-333, 2013. 櫂歌書房

 

2012

[原著論文]

Morimoto N, Kita S (co-first authors), Shimazawa M, Namimatsu H, Tsuruma K, Hayakawa K, Mishima K, Egashira N, Iyoda T, Horie I, Gotoh Y, Iwasaki K, Fujiwara M, Matsuda T, Baba A, Komuro I, Horie K, Takeda J, Iwamoto T*, Hara H* (*co-corresponding authors). Preferential involvement of Na+/Ca2+ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice. Biochem Biophys Res Commun. 429(3-4): 186-190, 2012.

Azuma YT, Nishiyama K, Kita S, Komuro I, Nakaurjima H, Iwamoto T, Takeuchi T. Na+/Ca2+ exchanger 2-heterozygote knockout mice display decreased acetylcholine release and altered colonic motility in vivo. Neurogastroenterol Motil. 24(12): e600-610, 2012.

Susa K, Kita S, Iwamoto T, Yang SS, Lin SH, Ohta A, Sohara E, Rai T, Sasaki S, Alessi DR, Uchida S. Effect of heterozygous deletion of WNK1 on the WNK-OSR1/SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vesseles. Clin Exp Nephrol. 16(4): 530-538, 2012.

[著書・総説]

岩本隆宏喜多紗斗美 結晶構造解析が解き明かすNa+/Ca2+交換輸送メカニズム 日薬理誌 140(5): 244, 2012.

喜多紗斗美岩本隆宏 Na+/Ca2+交換輸送体をめぐるトランスポートソーム 日薬理誌 139(5): 61-65, 2012.

岩本隆宏喜多紗斗美後藤雄輔堀江一郎藤井誠 平成23年度人体機能学IV (薬理学) 補講の実施報告 福岡大学医学紀要 39(3/4): 303-306, 2012.

柳田俊彦、安西尚彦、入江徹美、岩本隆宏 柳原延章、中野重行、村上学 なぜ服薬指導の場におけるコミュニケーション教育を重視するのか-医師の立場から薬局 63(12):3541-3545, 2012.

Fujii M, Kita S, Horie I, Gotoh Y, Iwamoto T. Cellular and Physiological Functions of Phosphoinositide-Metabolizing Enzymes. Med Bull Fukuoka Univ. 39(3/4): 281-287, 2012.

Horie I, Gotoh Y, Kita S, Fujii M, Iwamoto T. The Roles of Aquaporins in Inflammatory and Ischemic Diseases. Med Bull Fukuoka Univ. 39(3/4): 289-294, 2012.

岩本隆宏喜多紗斗美藤井誠堀江一郎後藤雄輔  薬理学テキスト(第3版)1-329, 2012. 櫂歌書房

岩本隆宏喜多紗斗美  実践治療薬「食塩感受性高血圧とNa+/Ca2+交換体 : 食塩負荷から血管トーヌス亢進へのイオン機序」 171-181, 2012.  株式会社金芳堂

岩本隆宏 利尿薬 イラストレイテッド薬理学 [原著5版] (編者:丸山敬・柳沢輝行)331-346, 2012.

 

2011

[原著論文]

Yamazaki D, Tabara Y, Kita S, Hanada H, Komazaki S, Naitou D, Mishima A, Nishi M, Yamaura H, Yamamoto S, Kakizawa S, Miyachi H, Yamamoto S, Miyata T, Kawano Y, Kamide K, Ogihara T, Hata A, Umemura S, Soma M, Takahashi N, Imaizumi Y, Miki T, Iwamoto T, Takeshima H. TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance. Cell Metab. 14(2): 231-241, 2011.

Nishioka K, Nishida M, Ariyoshi M, Jian Z, Saiki S, Hirano M, Nakaya M, Sato Y, Kita S, Iwamoto T, Hirano K, Inoue R, Kurose H. Cilostazol Suppresses Angiotensin Ⅱ-induced Vasoconstriction via Protein Kinase A-Mediated Phosphorylation of the Transient Receptor Potential Canonical 6 Channel. Arterioscler Thromb Vasc Biol. 31(10): 2278-2286, 2011.

Secondo A, Molinaro P, Pannaccione A, Esposito A, Cantile M, Lippiello P, Sirabella R, Iwamoto T, Di Renzo G, Annunziato L. Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants. Mol Pharmacol. 79(3): 558-568, 2011.

Matsui Y, Kita S, Iyoda T, Katsuragi T, Komuro I, Iwamoto T, Ohjimi H. Role of Na+/Ca2+ exchanger type 1 (NCX1) in the angiogenesis induced by Lipo-PGE1 in murine hindlimb ischemia model. Med Bull Fukuoka Univ. 38(2): 77-84,2011.

[著書・総説]

Iwamoto T, Kawasaki H. New molecular mechanisms for cardiovascular disease. J Pharmacol Sci. 116(4): 321-322, 2011.

Yamamoto S, Kita S, Iyoda T, Yamada T, Iwamoto T. New molecular mechanisms for cardiovascular disease: cardiac hypertrophy and cell-volume regulation. J Pharmacol Sci. 116(4): 343-349, 2011.

宮本賢一、岩本隆宏 無機イオン動態とトランスポーター・総論「トランスポートソームの世界」(京都廣川書店)226-230, 2011.

岩本隆宏喜多紗斗美 心血管系Ca2+トランスポートソーム:Na+/Ca2+交換体「トランスポートソームの世界」(京都廣川書店)326-335, 2011
.

 

2010

[原著論文]

Zhang J, Ren C, Chen L, Navedo MF, Antos LK, Kinsey SP, Iwamoto T, Philipson KD, Kotlikoff MI, Santana LF, Wier WG, Matteson DR, Blaustein MP. Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current, and lowers blood pressure. Am J Physiol Heart Circ Physiol: 298(5): H1472-1483, 2010.

Murata H, Hotta S, Sawada E, Yamamura H, Ohya S, Kita S, Iwamoto T, Imaizumi Y. Cellular Ca
2+ dynamics in urinary bladder smooth muscle from transgenic mice overexpressing Na+-Ca2+ exchanger. J Pharmacol Sci 19: 112(3): 373-377, 2010.

Yamamoto S, Iyoda T, Kita S, Yamada T, Iwamoto T. OSU-03012, a novel celecoxib derivative, induces cell swelling and shortens action potential duration in mouse ventricular cells. Biomed Res: 31 (6): 413-417, 2010.

Ichishima K, Yamamoto S, Iwamoto T, Ehara T. α1-Adrenoceptor-mediated PIP2 depletion inhibits activation of volume-regulated anion channels in mouse ventricular myocytes. Br J Pharmcol: 61(1): 193-206, 2010.

[著書・総説]

喜多紗斗美岩本隆宏. 食塩負荷から血管トーヌス亢進へのメカニズム:Na+/Ca2+交換体共役系の役割. 薬学雑誌 130(11): 1399-1405, 2010.

山本信太郎, 塩谷孝夫, 頴原嗣尚, 岩本隆宏. 心筋細胞を中心とした細胞の容積調節に関する評価法. 日薬理誌 135(6): 245-249, 2010.

伊豫田拓也, 喜多紗斗美岩本隆宏. マクロファージと食塩感受性高血圧の意外な関係日薬理誌 135(1): 42, 2010.   

 

2009

[原著論文]

Sakamoto K, Owada Y, Shikama Y, Wada I, Waguri S, Iwamoto T, and Kimura J. Involvement of Na+/Ca2+ exchanger in migration and contraction of rat cultured tendon fibroblasts. J Physiol 587(22): 5345-5359, 2009.

Saito R, Kaneko E, Tanaka Y, Honda K, Matsuda T, Baba A, Komuro I, Kita S, Iwamoto T, and Takano Y. Involvement of Na+/Ca2+ exchanger in pentylenetetrazol-induced convulsion by use of Na+/Ca2+ exchanger knockout mice. Biol Pharm Bull 32(11): 1928-1930, 2009.

Furuyama S, Uehara Y, Zhang B, Baba Y, Abe S, Iwamoto T, Miura S, and Saku K. Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men. J Atheroscler Thromb 16(3): 194-200, 2009.

Maeda S, Sakamoto K, Matsuoka I, Iwamoto T, Kimura J. Lysophosphatidylcholine increases Na+/Ca2+ exchanger expression via RhoB-geranylgeranylation in H9c2 cells. J Pharmacol Sci 109(4): 565-572, 2009.

Inokuchi Y, Shimazawa M, Nakajima Y, Komuro I, Matsuda T, Baba A, Araie M, Kita S, Iwamoto T, Hara H. A Na+/Ca2+ exchanger isoform, NCX1, is involved in retinal cell death after N-methyl-D-aspartate injection and ischemia-reperfusion. J Neurosci Res 87(4): 906-917, 2009.

[著書・総説]

岩本隆宏, 喜多紗斗美, 伊豫田拓也, 山本信太郎. 食塩負荷から血管トーヌス亢進へのシグナル伝達機構 ―Na+ポンプ・Na+/Ca2+交換輸送体の機能協関―. Transportsome (10): 17-20, 2009.

伊豫田拓也, 喜多紗斗美, 山本信太郎, 小室一成, 西山成, 岩本隆宏. アルドステロンが誘導する心臓リモデリングにおけるNa+/Ca2+交換輸送体(NCX1)の役割. 血管 32(4): 99-102, 2009.

Blaustein MP, Zhang J, Chen L, Song H, Raina H, Kinsey SP, Izuka M, Iwamoto T, Kotlikoff MI, Lingrel JB, Philipson KD, Wier WG, Hamlyn JM. The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension 53(2): 291-298, 2009.

岩本隆宏, 喜多紗斗美, 伊豫田拓也. Na+/Ca2+交換体を分子標的とした新規Ca2+調節薬の開発. 遺伝子医学MOOK 12: 248-254, 2009.

Yamamoto S, Yamada T, Iyoda T, Kita S, Iwamoto T. Role of Cl- Channels and Transporters in the Cardiac Cell Volume Homeostasis. Med Bull Fukuoka Univ 36(4): 243-255, 2009.

Yamada T, Kita S, Iyoda T, Yamamoto S, Iwamoto T. The Role of Sodium, Calcium, and Magnesium Transport in the Renal Distal Tubule. Med Bull Fukuoka Univ 36(4): 257-262, 2009.

岩本隆宏. 利尿薬 イラストレイテッド 薬理学 [原著4版] (編者: 九山敬・柳沢輝行) 306-321, 2009.

     

2008

[原著論文]

Mima M, Kawai C, Paku K, Tomoo K, Ishida T, Sugiyama S, Matsumura H, Kitatani T, Yoshikawa HY, Maki S, Adachi H, Takano K, Murakami S, Inoue T, Mori Y, Kita S, Iwamoto T. Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger. Acta Crystallogr Sect F Struct Biol Cryst Commun 64(Pt12): 1125-1127, 2008.

Uehara Y, Yamada T, Baba Y, Miura S, Abe S, Kitajima K, Higuchi MA, Iwamoto T, Saku K. ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer's brain. Brain Res 1217: 239-246, 2008.

[著書・総説]

Kita S, Iyoda T, Iwamoto T. Cardiovascular Na+/Ca2+ exchanger: Pathophysiologic roles and therapeutic potentials. Med Bull Fukuoka Univ 35(4): 211-218, 2008.

辛島詠士, 平松伸一, 小田代敬太, 赤司浩一, 丸山徹, 山中淳, 岩本隆宏, 喜多紗斗美, 平野勝也, 平野真弓, 金出英夫. 平滑筋におけるcAMPシグナル伝達系の新展開 Na+/Ca2+交換体の関与. 臨牀と研究 85(9): 1356-1359, 2008.

岩本隆宏, 喜多紗斗美, 伊豫田拓也. 心血管系Na+/Ca2+交換体の構造・機能・病態生理. 日臨生理会誌 38: 195-201, 2008.

   

2007

[原著論文]

Karashima E, Nishimura J, Iwamoto T, Hirano K, Hirano M, Kita S, Harada M, Kanaide H. Involvement of Na+-Ca2+ exchanger in cAMP-mediated relaxation in mice aorta: evaluation using transgenic mice. Br J Pharmacol 150(4): 434-444, 2007.

Ifuku M, Farber K, Okuno Y, Yamakawa Y, Miyamoto T, Nolte C, Merrino VF, Kita S, Iwamoto T, Komuro I, Wang B, Cheung G, Ishikawa E, Ooboshi H, Bader M, Wada K, Kettenmann H, Noda M. Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci 27(48): 13065-13073, 2007.

Niu CF, Watanabe Y, Ono K, Iwamoto T, Yamashita K, Satoh H, Urushida T, Hayashi H, Kimura J. Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes. Eur J Pharmacol 573(1-3): 161-169, 2007.

Li JP, Kajiya H, Okamoto F, Nakao A, Iwamoto T, Okabe K. Three Na+/Ca2+ exchanger (NCX) variants are expressed in mouse osteoclasts and mediate calcium transport during bone resorption. Endocrinology 148(5): 2116-2125, 2007.

Du CK, Morimoto S, Nishii K, Minakami R, Ohta M, Tadano N, Lu QW, Wang YY, Zhan DY, Mochizuki M, Kita S, Miwa Y, Takahashi-Yanaga F, Iwamoto T, Ohtsuki I, Sasaguri T. Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation. Circ Res 101(2): 185-194, 2007.

Hinata M, Matsuoka I, Iwamoto T, Watanabe Y, Kimura J. Mechanism of Na+/Ca2+ exchanger activation by hydrogen peroxide in guinea-pig ventricular myocytes. J Pharmacol Sci 103(3): 283-292, 2007.

Zhao Y, Migita K, Sato C, Usune S, Iwamoto T, Katsuragi T. Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells. J Pharmacol Sci 105(1): 57-65, 2007.

[著書・総説]

岩本隆宏, 喜多紗斗美. 心血管病における1Na+/Ca2+交換体(NCX1)の役割. 日薬理誌 129(4): 262-265, 2007.

岩本隆宏, 喜多紗斗美. Na+/Ca2+ exchanger. 腎と透析 63(4): 474-477, 2007.

岩本隆宏, 喜多紗斗美. 食塩感受性高血圧におけるNCX1の役割. 医学のあゆみ 223: 1141-1145, 2007.

岩本隆宏. 心筋Na+/Ca2+交換体(NCX1)の構造と機能-最近の進歩-. Transportsome(6): 8-10, 2007.

Iwamoto T, Watanabe Y, Kita S, Blaustein MP. Na+/Ca2+ exchange inhibitors: a new class of calcium regulators. Cardiovasc Hematol Disord Drug Targets 7(3): 188-198, 2007.

Iwamoto T. Na+/Ca2+ exchange as a drug target -Insight from molecular pharmacology and genetic engineering. Ann N Y Acad Sci 1099: 516-528, 2007.

 

 


 



Department of Pharmacology, Fukuoka University. All rights reserved.