2022年度業績集

原著

  1. Concomitant use of an immunomodulator with ustekinumab as an induction therapy for Crohn's disease: A systematic review and meta-analysis.Yoshihara T, Shinzaki S, Amano T, Iijima H, Takehara T, Inoue N, Uchino M, Esaki M, Kobayashi T, Saruta M, Sugimoto K, Nakamura S, Hata K, Hirai F, Hiraoka S, Fujii T, Matsuura M, Matsuoka K, Watanabe K, Nakase H, Watanabe M. J Gastroenterol Hepatol.36（7）：1744-1753， 2021
  2. Adrenomedullin for steroid-resistant ulcerative colitis: a randomized, double-blind, placebo-controlled phase-2a clinical trial.Kita T, Ashizuka S, Ohmiya N, Yamamoto T, Kanai T, Motoya S, Hirai F, Nakase H, Moriyama T, Nakamura M, Suzuki Y, Kanmura S, Kobayashi T, Ohi H, Nozaki R, Mitsuyama K, Yamamoto S, Inatsu H, Watanabe K, Hibi T, Kitamura K. J Gastroenterol.56(2):147-157, 2021
  3. Novel ultrathin double-balloon endoscopy for the diagnosis ofsmall-bowel diseases: a multicenter nonrandomized study.Nakamura M, Yano T, Esaki M, Oka S, Mitsui K, Hirai F, Kawasaki K, Fujishiro M, Torisu T, Tanaka S, Iwakiri K, Kishi M, Matsumoto T, Yamamoto H.Endosc.53(8):802-814, 2021
  4. Intestinal cancer in patients with Crohn's disease: A systematic review and meta-analysis.Uchino M, Ikeuchi H, Hata K, Minagawa T, Horio Y, Kuwahara R, Nakamura S, Watanabe K, Saruta M, Fujii T, Kobayashi T, Sugimoto K, Hirai F, Esaki M, Hiraoka S, Matsuoka K, Shinzaki S, Matsuura M, Inoue N, Nakase H, Watanabe M.J Gastroenterol Hepatol.36（2）：329-336, 2021
  5. Tag-less patency capsule for suspected small bowel stenosis: Nationwide multicenter prospective study in Japan.Nakamura M, Watanabe K, Ohmiya N, Hirai F, Omori T, Tokuhara D, Nakaji K, Nouda S, Esaki M, Sameshima Y, Goto H, Terano A, Tajiri H, Matsui T, J-POP study groupDig Endosc.33（1）:151-161, 2021
  6. Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study.Shinzaki S, Matsuoka K, Tanaka H, Takeshima F, Kato S, Torisu T, Ohta Y, Watanabe K, Nakamura S, Yoshimura N, Kobayashi T, Shiotani A, Hirai F, Hiraoka S, Watanabe M, Matsuura M, Nishimoto S, Mizuno S, Iijima H, Takehara T, Naka T, Kanai T, Matsumoto T.J Gastroenterol.56（6）：560-569, 2021
  7. Does anti-tumor necrosis factor alpha prevent the recurrence of Crohn's disease? Systematic review and meta-analysis. Uchino M, Ikeuchi H, Hata K, Minagawa T, Horio Y, Kuwahara R, Nakamura S, Watanabe K, Saruta M, Fujii T, Kobayashi T, Sugimoto K, Hirai F, Esaki M, Hiraoka S, Matsuoka K, Shinzaki S, Matsuura M, Inoue N, Nakase H, Watanabe M. J Gastroenterol Hepatol.36(4):864-872, 2021
  8. Physician-patient communication affects patient satisfaction in treatment decision-making: a structural equation modelling analysis of a web-based survey in patients with ulcerative colitis.Matsuoka K, Ishikawa H, Nakayama T, Honzawa Y, Maemoto A, Hirai F, Ueno F, Sato N, Susuta Y, Hibi T. J Gastroenterol.56(9):843-855, 2021
  9. Discontinuation of infliximab in patients with ulcerative colitis in remission (HAYABUSA): a multicentre, open-label, randomised controlled trial.Kobayashi T, Motoya S, Nakamura S, Yamamoto T, Nagahori M, Tanaka S, Hisamatsu T, Hirai F, Nakase H, Watanabe K, Matsumoto T, Tanaka M, Abe T, Suzuki Y, Watanabe M, Hibi T, HAYABUSA Study GroupLancet Gastroenterol Hepatol.6(6):429-437, 2021
  10. Identifying Bleeding Etiologies by Endoscopy Affected Outcomes in 10,342 Cases With Hematochezia: CODE BLUE-J Study. Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Fukuzawa M, Itoi T, Uemura N, Kawai T, Kaise M.Am J Gastroenterol.116(11):2222-2234, 2021
  11. Outcomes in high and low volume hospitals in patients with acute hematochezia in a cohort study. Ishii N, Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Omata F, Shiratori Y, Imamura N, Yano T, Kaise M.Sci Repdoi: 10.1038/s41598-021-99832-6., 2021
  12. Treatment strategies for reducing early and late recurrence of colonic diverticular bleeding based on stigmata of recent hemorrhage: a large multicenter study. Gobinet MS, Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Uemura N, Itawa E, Sugimoto M, Fukuzawa M, Kawai T, Kaise M, Itoi T.Gastrointest Endosc.doi:10.1016/j.gie.2021.12.023., 2021
  13. Elobixibat, an ileal bile acid transporter inhibitor, ameliorates non-alcoholic steatohepatitis in miceYamauchi R, Takedatsu H, Yokoyama K, Yamauchi E, Kawashima M, Nagata T, Uchida Y, Kitaguchi T, Higashi T, Fukuda H, Tsuchiya N, Takata K, Tanaka T, Morihara D, Takeyama Y, Shakado S, Sakisaka S, Hirai F.Hepatol Int.15(2):392-404, 2021
  14. Irsogladine maleate alters expression of a tight junction protein in portal hypertensive gastropathy. Yokoyama K, Irie M, Tsuchiya N, Yamauchi E, Kawashima M, Miyayama T, Fukuda H, Yamauchi R, Umeda K, Takata K, Tanaka T, Inomata S, Morihara D, Takeyama Y, Shakado S, Sakisaka S, Hirai F.J Gastroenterol Hepatol.36(5):1208-1215, 2021
  15. 本邦における小腸狭窄が疑われた患者に対するタグ非搭載　パテンシーカプセル検査の全国多施設前向き調査中村正直、渡辺憲治、大宮直木、平井郁仁、大森鉄平、徳原大介、中路 幸之助、能田貞治、江崎幹宏、鮫島 由規則、後藤秀実、寺野　彰、田尻久雄、松井敏幸Gastroenterol Endosc.63(10):2242-2252, 2021
  16. Evidence-based clinical practice guidelines for inflammatory bowel disease 2020.Nakase H, Uchino M, Shinzaki S, Matsuura M, Matsuoka K, Kobayashi T, Saruta M, Hirai F, Hata K, Hiraoka S, Esaki M, Sugimoto K, Fuji T, Watanabe K, Nakamura S, Inoue N, Itoh T, Naganuma M, Hisamatsu T, Watanabe M, Miwa H, Enomoto N, Shimosegawa T, Koike K.J Gastroenterol.56（5）：489-526，2021
  17. クローン病小腸狭窄に対する内視鏡的バルーン拡張術ガイドライン(小腸内視鏡診療ガイドライン追補)山本博徳、矢野智則、荒木昭博、江﨑幹宏、大塚和朗、大宮直木、岡　志郎、仲瀬裕志、馬場重樹、平井郁仁、細江直樹、松田知己、三井啓吾、渡辺憲治、緒方晴彦、勝木伸一、松本主之、藤城光弘、藤本一眞、井上晴洋、久松理一、日本消化器内視鏡学会、日本消化器内視鏡学会ガイドライン委員会、ワーキング委員会、日本炎症性腸疾患学会、日本消化管学会、日本消化器病学会、日本小腸学会、厚生労働科学研究費補助金難治性疾患政策研究事業「難治性炎症性腸管障害に関する調査研究」班Gastroenterol Endosc.63(10):2253-2275,2021
  18. Long-term outcomes of endoscopic balloon dilation for intestinal strictures in patients with Crohn's disease during maintenance treatment with anti-tumor necrosis factor alpha antibodies.Takeda T, Kishi M, Takatsu N, Takada Y, Beppu T, Miyaoka M, Hisabe T, Ueki T, Arima H, Hirai F, Yao K. Dig Endosc.34(3):517-525, 2022
  19. Male-specific Association between Iron and Lipid Metabolism Changes and Erythroferrone after Hepatitis C Virus Eradication.Inomata S, Morihara D, Anan A, Yamauchi E, Yamauchi R, Takata K, Tanaka T, Yokoyama K, Takeyama Y, Irie M, Shakado S, Sohda T, Sakisaka S, Hirai F.Intern Med.61(4):461-467, 2022
  20. Endoscopic direct clipping versus indirect clipping for colonic diverticular bleeding: A large multicenter cohort study. Kishino T, Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Kaise M.United European Gastroenterol J.doi: 10.1002/ueg2.12197., 2022
  21. Suppression of Local Tumor Progression in Perivascular Hepatocellular Carcinoma by Combination Therapy with Radiofrequency Ablation and Percutaneous Ethanol Injection: A Propensity Score Matching AnalysisTakata K, Tanakaa T, Anana A, Fukunaga A, Nagata T, Fukuda H, Yamauchi R, Kunimoto H, Yokoyama K, Morihara D, Takeyama Y, Iwata K, Shakado S, Sakisaka S, Hirai F.Oncologydoi: 10.1159/000522374., 2022
  22. AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 studyMatsuoka K, Watanabe M, Ohmori T, Nakajima K, Ishida T, Ishiguro Y, Kanke K, Kobayashi K, Hirai F, Watanabe K, Mizusawa H, Kishida S, Miura Y, Ohta A, Kajioka T, Hibi T; AJM300 Study Group.Lancet Gastroenterol Hepatol. doi: 10.1016/S2468-1253(22)00022-X., 2022
  23. Efficacy and safety of filgotinib as induction and maintenance therapy for Japanese patients with moderately to severely active ulcerative colitis: a post-hoc analysis of the phase 2b/3 SELECTION trialHibi T, Motoya S, Hisamatsu T, Hirai F, Watanabe K, Matsuoka K, Saruta M, Kobayashi T, Feagan BG, Tasset C, Besuyen R, Yun C, Crans G, Zhang J, Kondo A, Watanabe M.Intest Res. doi: 10.5217/ir.2021.00143., 2022
  24. Interim analysis of a multicenter registry study of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS)Nakase H, Hayashi Y, Hirayama D, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Abukawa D, Hisamatsu T; J-COSMOS group.J Gastroenterol. 57(3):174-184, 2022
  25. Role of Serum Proteinase 3 Antineutrophil Cytoplasmic Antibodies in the Diagnosis, Evaluation of Disease Severity, and Clinical Course of Ulcerative ColitisImakiire S, Takedatsu H, Mitsuyama K, Sakisaka H, Tsuruta K, Morita M, Kuno N, Abe K, Funakoshi S, Ishibashi H, Yoshioka S, Torimura T, Hirai F.Gut Liver. 16(1):92-100, 2022
  26. Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Crohn's DiseaseSands BE, Peyrin-Biroulet L, Kierkus J, Higgins PDR, Fischer M, Jairath V, Hirai F, D'Haens G, Belin RM, Miller D, Gomez-Valderas E, Naegeli AN, Tuttle JL, Pollack PF, Sandborn WJ.Gastroenterology. 162(2):495-508, 2022

症例報告

  1. Novel Endoscopic Therapy for Gastric Varices Using Direct Forward-Viewing Endoscopic Ultrasonography.Yokoyama K, Miyayama T, Uchida Y, Fukuda H, Yamauchi R, Tsuchiya N, Umeda K, Takata K, Tanaka T, Inomata S, Morihara D, Takeyama Y, Shakado S, Sakisaka S, Hirai F.Case Rep Gastroenterol.15（1）：28-34,2021
  2. Gastroesophageal Varices and Hyperplastic Nodules of the Liver in a Patient with Anorexia Nervosa.Takata K, Nagata T, Uchida Y, Kitaguchi T, Higashi T, Fukuda H, Yamauchi R, Tsuchiya N, Tanaka T, Yokoyama K, Morihara D, Takeyama Y, Shakado S, Hamada Y, Yoshimitsu K, Sakisaka S, Hirai F.Intern Med.60(19):3017-3112,2021
  3. Eosinophilic Granuloma of the Liver Mimicking Metastatic Liver Tumor: A Case Report.Uchida Y, Yokoyama K, Higashi T, Kitaguchi T, Fukuda H, Yamauchi R, Tsuchiya N, Fukunaga A, Umeda K, Takata K, Tanaka T, Takeyama Y, Shakado S, Sakisaka S, Hayashi H, Hamada Y, Nabeshima K, Hirai F.Intern Med.doi:10.2169/internalmedicine.8438-21. 2021
  4. A case of episodic angioedema with eosinophilia in an elderly woman with primary biliary cholangitis.Iwashita H, Shakado S, Yasuda H, Tanabe T, Yamaguchi M, Irie M, Hirai F. Clin J Gastroenterol.14(3):836-841,2021
  5. Multiple focal fatty changes in the liver in patients with porphyria cutanea tarda: A case series and review of the literature.Takata K, Fukunaga A, Nishizawa S, Uchida Y, Fukuyama M, Nagata T, Higashi T, Fukuda H, Yamauchi R, Tanaka T, Yokoyama K, Morihara D, Takeyama Y, Shakado S, Sakisaka S, Hirai F. J Clin Ultrasound.doi: 10.1002/jcu.23108. 2021
  6. Mass-forming adenomyomatosis in extrahepatic bile duct.Ishida Y, Okabe Y, Hisaka T, Naito Y, Torimura T.Gastrointest Endosc.93(2):522-524,2021
  7. Duckbill-type antireflux self-expandable metal stent placement for post-choledochojejunostomy reflux cholangitisKoga T, Hijioka S, Ishikawa Y, Ito K, Harai S, Okusaka T, Saito Y.Endoscopy53(5):E174-E176,2021
  8. Endoscopic ultrasound-guided choledochoduodenostomy without fistula dilation using a novel fully covered metallic stent with a 5.9-Fr ultra-thin delivery systemKoga T, Hijioka S, Hisada Y, Maruki Y, Nagashio Y, Okusaka T, Saito Y.Endoscopy53(6):E223-E225,2021
  9. 腫瘍随伴症候群としての発熱を伴ったびまん型肝未分化癌の一剖検例福田　祥、二村　聡、山内　涼、吉村雅代、川島素子、福田洋美、高田和英、田中　崇、森原大輔、横山圭二、竹山康章、釈迦堂敏、鍋島一樹、向坂彰太郎、平井郁仁福岡大学医学紀要48(2), 143-147, 2021
  10. Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease:First Reported Case and a Listerature Review.Ishibashi H, Imakiire S, Goto M, Nomaru R, Shibata M, Matsuika H, Yasuda H, Yamashima T, Sakisaka H, Tanabe T, Matsuoka S, Kuno N, Abe K, Funakoshi S, Takamatsu Y, Hirai F and Takeshita M.Intern Med.61(3):329-334,2022
  11. Operative findings of the migrated stent into the abdominal cavity following endoscopic ultrasound-guided hepaticogastrostomy: Anchoring force of a novel self-expandable metal stent with an anti-migration system (with video)Koga T, Ishida Y, Hirai F.J Hepatobiliary Pancreat Sci. doi: 10.1002/jhbp.1109., 2022

総説

  1. 潰瘍性大腸炎平井郁仁臨牀と研究98(5):9（525）-13（529）,2021
  2. IBD診療現場のPros & Cons 生物学的製剤による寛解維持中に５-ASA製剤を続けるべきか？平井郁仁IBD Research15(1):43-47,2021
  3. 炎症性腸疾患のモニタリングにおける大腸内視鏡の意義と実際平井郁仁、久能宣昭、阿部光市日本消化器病学会雑誌118(3):203-211,2021
  4. 第４章　消化器系の基本薬の使い分け 潰瘍性大腸炎への免疫抑制薬はどう選ぶ？平井郁仁月刊薬事　臨時増刊号63(7):201(1381)-206(1386),2021
  5. 【IBDの診断と治療】クローン病の診断基準と鑑別疾患平井郁仁消化器内科3（4）：21-26，2021
  6. 小腸　治療　内視鏡的バルーン拡張術平井郁仁胃と腸56（5）：707，2021
  7. 「プレフレイル高齢大腸がん患者のための臨床的提言」 支持・緩和医療に関する提言石黒　洋、石橋英樹、山口　崇、綿貫成明、華井明子、桜井なおみ、辻　哲也日本大腸肛門病学会雑誌74（6）：349-356,2021
  8. バルーン内視鏡による小腸腫瘍の診断と治療阿部光市、久能宣昭、石橋英樹、濱田義浩、濱﨑　慎、平井郁仁消化器内科3(12), 76-86, 2021
  9. 炎症性腸疾患の画像所見と鑑別診断船越禎広、阿部光市、久能宣昭、柴田　衛、能丸遼平、山嶋友実、保田秀生、松岡弘樹、今給黎 宗、松岡　賢、田辺太郎、向坂秀人、石橋英樹、平井郁仁胃と腸56(12), 1519-1526, 2021
  10. A．疾患マネージメントに大きく変革がもたらされた病態 小腸狭窄性病変平井郁仁消化器内視鏡33(12)：1833-1842,2021
  11. Medical Oncologistが知っておくべき、肝胆膵領域における最新の内視鏡処置古賀毅彦、 肱岡　範,、真下翔太、河原　駿、村嶋佑美、川崎佑輝、北村英俊、原井正太、丸木雄太、大場彬博、永塩美邦、近藤俊輔、森実千種、上野秀樹、奥坂 拓志腫瘍内科27(2):224-232,2021
  12. 胆膵内視鏡－介助者に必要な知識－石田祐介、平井郁仁九州消化器内視鏡技師会会誌33:38-45,2021
  13. 内視鏡介助技術向上に向けて～大腸内視鏡診療を中心に～船越禎広、平井郁仁九州消化器内視鏡技師会会誌33:46-48,2021
  14. 【炎症性腸疾患update-診断・治療の最新知見-】診断とモニタリングの進歩　小腸バルーン内視鏡とカプセル内視鏡の進歩山嶋 友実, 平井 郁仁, 阿部 光市日本臨床80(3):420-426, 2022
  15. 【炎症性腸疾患の粘膜治癒を再考する】Crohn病における小腸粘膜治癒評価の意義　X線の立場から久能 宣昭, 阿部 光市, 船越 禎広, 石橋 英樹, 平井 郁仁胃と腸57(2):165-172, 2022
  16. 【こんなときどうする】前投薬によるトラブル発生時の対応　キシロカイン、抗コリン薬、鎮静薬、プロポフォールなど船越 禎広, 山嶋 友実, 柴田 衛, 能丸 遼平, 今給黎 宗, 向坂 秀人, 久能 宣昭, 石橋 英樹, 平井 郁仁消化器内視鏡34(3):339-344,2022

著書

  1. 腸管Behcet病、単純性潰瘍 専門医のための消化器病学　第３版平井郁仁　（分担）　 医学書院pp.210-214,2021
  2. 11.内視鏡的拡張術　①クローン病狭窄病変への考え方とEBDの適応、②EBDの方法、③EBDの治療成績と合併症 クローン病の診療ガイドライン 第3版 （NPO法人 日本炎症性腸疾患協会（CCFJ）編)平井郁仁（分担） 文光堂pp.64-66,2021
  3. 第１章　診断と分類 1. 概念・疫学、2. 診断へのアプローチ、3. 診断確定と鑑別疾患、4. 病態（病型、病期、重症度）の分類 潰瘍性大腸炎の診療ガイドライン 第4版 （NPO法人 日本炎症性腸疾患協会（CCFJ）編平井郁仁（分担） 文光堂pp.10-16,2021
  4. 診断のTips No.42　ERCP下細胞診　適切な検体処理を行っていますか？ 教科書では教えてくれない！ 私の消化器内視鏡 Tips vol.2石田祐介（分担） 医学書院pp.44, 2021

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