業績集

原著

  1. Endoscopic direct clipping versus indirect clipping for colonic diverticular bleeding: A large multicenter cohort study. Kishino T, Nagata N, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kawagishi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Kaise M.United European Gastroenterol J. 10(1):93-103,2022
  2. AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 studyMatsuoka K, Watanabe M, Ohmori T, Nakajima K, Ishida T, Ishiguro Y, Kanke K, Kobayashi K, Hirai F, Watanabe K, Mizusawa H, Kishida S, Miura Y, Ohta A, Kajioka T, Hibi T; AJM300 Study Group.Lancet Gastroenterol Hepatol. 7(7)：648-657,2022
  3. Interim analysis of a multicenter registry study of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS)Nakase H, Hayashi Y, Hirayama D, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Abukawa D, Hisamatsu T; J-COSMOS group.J Gastroenterol. 57(3):174-184, 2022
  4. Perspectives of East Asian patients and physicians on complementary and alternative medicine use for inflammatory bowel disease: results of a cross-sectional, multinational study.Eun Soo Kim, Chung Hyun Tae, Sung-Ae Jung, Dong Il Park, Jong Pil Im, Chang Soo Eun, Hyuk Yoon, Byung Ik Jang, Ogata H, Fukuhara K, Hirai F, Ohtsuka K, Jing Liu, Qian Cao, Clinical Research Committee of the Asian Organization for Crohn’s and Colitis Intest Res 20(2):192-202,2022
  5. Role of Serum Proteinase 3 Antineutrophil Cytoplasmic Antibodies in the Diagnosis, Evaluation of Disease Severity, and Clinical Course of Ulcerative ColitisImakiire S, Takedatsu H, Mitsuyama K, Sakisaka H, Tsuruta K, Morita M, Kuno N, Abe K, Funakoshi S, Ishibashi H, Yoshioka S, Torimura T, Hirai F.Gut Liver 16(1):92-100, 2022
  6. Guidelines for endoscopic balloon dilation in treating Crohn's disease-associated small intestinal strictures (supplement to the Clinical Practice Guidelines for Enteroscopy)Yamamoto H, Yano T, Araki A, Esaki M, Ohtsuka K, Ohmiya N, Oka S, Nakase H, Bamba S, Hirai F, Hosoe N, Matsuda T, Mitsui K, Watanabe K, Ogata H, Katsuki S, Matsumoto T, Fujishiro M, Fujimoto K, Inoue H.Dig Endosc 34(7):1278-1296,2022
  7. Treatment Patterns in Newly Diagnosed Patients with Crohn's Disease Who Received Biologics Following Diagnosis: A Nationwide, Retrospective, Longitudinal, Observational Study Using a Medical Claims Database in JapanHirai F, Uda A, Ota M, Takemura Y, Tanaka K, Iwakiri R.Digestion 30:1-12,2022
  8. Comparison of Efficacy and Safety of Atezolizumab Plus Bevacizumab and Lenvatinib as First-Line Therapy for Unresectable Hepatocellular Carcinoma: A Propensity Score Matching AnalysisNiizeki T, Tokunaga T, Takami Y, Wada Y, Harada M, Shibata M, Nakao K, Sasaki R, Hirai F, Shakado S, Yoshizumi T, Itoh S, Yatsuhashi H, Bekki S, Ido A, Mawatari S, Honda K, Sugimoto R, Senju T, Takahashi H, Kuwashiro T, Maeshiro T, Nakamuta M, Aratake Y, Yamashita T, Otsuka Y, Matsumoto S, Sohda T, Shimose S, Murotani K, Tanaka Y.Target Oncol. 17(6)：643-653,2022
  9. Adrenomedullin for biologic-resistant Crohn's disease: A randomized, double-blind, placebo-controlled phase 2a clinical trialKita T, Ashizuka S, Takeda T, Matsumoto T, Ohmiya N, Nakase H, Motoya S, Ohi H, Mitsuyama K, Hisamatsu T, Kanmura S, Kato N, Ishihara S, Nakamura M, Moriyama T, Saruta M, Nozaki R, Yamamoto S, Inatsu H, Watanabe K, Kitamura K.J Gastroenterol Hepatol 37(11):2051-2059,2022
  10. Nationwide cohort study identifies clinical outcomes of angioectasia in patients with acute hematocheziaKobayashi M, Akiyama S, Narasaka T, Kobayashi K, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kobayashi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Tsuchiya K, Kaise M, Nagata N.J Gastroenterol. doi: 10.1007/s00535-022-01945-w. Online ahead of print.2022
  11. Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: a large-scale multicenter cohort studyKobayashi K, Nagata N, Furumoto Y, Yamauchi A, Yamada A, Omori J, Ikeya T, Aoyama T, Tominaga N, Sato Y, Kishino T, Ishii N, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Kaise M; CODE BLUE-J study collaborators.Endosc 54(8):735-744,2022
  12. Suppression of Local Tumor Progression in Perivascular Hepatocellular Carcinoma by Combination Therapy with Radiofrequency Ablation and Percutaneous Ethanol Injection: A Propensity Score Matching AnalysisTakata K, Tanakaa T, Anana A, Fukunaga A, Nagata T, Fukuda H, Yamauchi R, Kunimoto H, Yokoyama K, Morihara D, Takeyama Y, Iwata K, Shakado S, Sakisaka S, Hirai F.Oncology 100（6）：303-312,2022
  13. Clinical Utility of Ultrasound-Guided Attenuation Parameter for the Detection and Quantification of Hepatic Steatosis in Patients with Fatty Liver Diagnosed by Computed TomographyIwashita H, Shakado S, Yoshimaru N, Tanaka H, Koto F, Tanaka T, Takata K, Yokoyama K, Yamaguchi M, Irie M, Hirai F.Ultrasound Med Biol 48(7):1282-1289,2022
  14. Long-term outcomes of hemostatic therapy for variceal bleeding and the challenge pending in the post-direct-acting antivirals era.Shibata K, Yokoyama K, Yamauchi R, Matsumoto K, Himeno S, Nagata T, Higashi T, Kitaguchi T, Fukuda H, Tsuchiya N, Fukunaga A, Takata K, Tanaka T, Takeyama Y, Shakado S, Sakisaka S, Hirai F. Acta Gastroenterol Belg 85(1):7-14,2022
  15. Pretreatment Modified Albumin-Bilirubin Grade Is an Important Predictive Factor Associated with the Therapeutic Response and the Continuation of Atezolizumab plus Bevacizumab Combination Therapy for Patients with Unresectable Hepatocellular CarcinomaTanaka T, Takata K, Yokoyama K, Fukuda H, Yamauchi R, Fukunaga A, Shakado S, Sakisaka S, Hirai F.Curr Oncol. 29(7):4799-4810,2022
  16. Long-Term Effects of Rifaximin on Patients with Hepatic Encephalopathy: Its Possible Effects on the Improvement in the Blood Ammonia Concentration Levels, Hepatic Spare Ability and Refractory Ascites Yokoyama K, Fukuda H, Yamauchi R, Higashi M, Miyayama T, Higashi T, Uchida Y, Shibata K, Tsuchiya N, Fukunaga A, Umeda K, Takata K, Tanaka T, Shakado S, Sakisaka S, Hirai F. Medicina (Kaunas). 58(9):1276,2022
  17. Multipolar radiofrequency ablation via three bipolar electrodes with C-arm type X-ray fluoroscopy assistance for hepatocellular carcinoma: An observational studyTanaka T, Anan A, Takata K, Fukuda H, Yamauchi R, Inomata S, Yokoyama K, Takeyama Y, Shakado S, Sakisaka S, Hirai F. Medicine (Baltimore) 101(38):e30725. doi: 10.1097/MD.0000000000030725.
  18. Trends in hepatocellular carcinoma incident cases in Japan between 1996 and 2019Nakano M, Yatsuhashi H, Bekki S, Takami Y, Tanaka Y, Yoshimaru Y, Honda K, Komorizono Y, Harada M, Shibata M, Sakisaka S, Shakado S, Nagata K, Yoshizumi T, Itoh S, Sohda T, Oeda S, Nakao K, Sasaki R, Yamashita T, Ido A, Mawatari S, Nakamuta M, Aratake Y, Matsumoto S, Maeshiro T, Goto T, Torimura T.Sci Rep 12(1):1517,2022
  19. Standardized Methods Using EUS-guided Fine-needle Biopsy and a Minimal Medium Creates Three Pancreatic Cancer OrganoidsIshida Y, Tsunoda T, Hamada Y, Tsuchiya N, Koga T, Kitaguchi T, Matsumoto K, Matsumoto S, Sasaki T, Nakashima R, Ishii F, Kajiwara M, Shirasawa S, Hasegawa S, Hirai F.Anticancer Res 42(8): 4103-4109,2022
  20. Proportion of unresectable pancreatic cancer specimens obtained by endoscopic ultrasound-guided tissue acquisition meeting the OncoGuide™ NCC Oncopanel System analysis suitability criteria: a single-arm, phase II clinical trial.Hisada Y, Hijioka S, Ikeda G, Maehara K, Hashimoto T, Kitamura H, Harai S, Yoshinari M, Kawasaki Y, Murashima Y, Koga T, Takeshita K, Maruki Y, Ohba A, Nagashio Y, Kondo S, Morizane C, Ueno H, Saito Y, Yatabe Y, Okusaka T.J Gastroenterol 57(12):990-998,2022
  21. A novel endoscopic technique using fully covered self-expandable metallic stents for benign strictures after hepaticojejunostomy: the saddle-cross technique (with video).Kawasaki Y, Hijioka S, Nagashio Y, Ohba A, Maruki Y, Maehara K, Yoshinari M, Hisada Y, Harai S, Kitamura H, Murashima Y, Koga T, Kawahara S, Kondo S, Morizane C, Ueno H, Ushio J, Tamada K, Sugawara S, Sone M, Takamoto T, Nara S, Ban D, Esaki M, Arai Y, Shimada K, Saito Y, Okusaka TSurg Endosc. 36(12):9001-9010,2022
  22. Efficacy and safety of filgotinib as induction and maintenance therapy for Japanese patients with moderately to severely active ulcerative colitis: a post-hoc analysis of the phase 2b/3 SELECTION trialHibi T, Motoya S, Hisamatsu T, Hirai F, Watanabe K, Matsuoka K, Saruta M, Kobayashi T, Feagan BG, Tasset C, Besuyen R, Yun C, Crans G, Zhang J, Kondo A, Watanabe M.Intest Res. 21(1):110-125, 2023
  23. Thiopurine naivety at tacrolimus induction is a predictor of long-term remission in patients with intractable ulcerative colitis who responded to tacrolimusTakatsu N, Hisabe T, Kishi M, Takeda T, Yasukawa S, Koga A, Kinjo K, Hirai F, Ueki T, Yao K.J Gastroenterol Hepatol 38(1):52-60,2023
  24. Timing of colonoscopy in acute lower GI bleeding: a multicenter retrospective cohort studyShiratori Y, Ishii N, Aoki T, Kobayashi K, Yamauchi A, Yamada A, Omori J, Aoyama T, Tominaga N, Sato Y, Kishino T, Sawada T, Murata M, Takao A, Mizukami K, Kinjo K, Fujimori S, Uotani T, Fujita M, Sato H, Suzuki S, Narasaka T, Hayasaka J, Funabiki T, Kinjo Y, Mizuki A, Kiyotoki S, Mikami T, Gushima R, Fujii H, Fuyuno Y, Gunji N, Toya Y, Narimatsu K, Manabe N, Nagaike K, Kinjo T, Sumida Y, Funakoshi S, Kobayashi K, Matsuhashi T, Komaki Y, Miki K, Watanabe K, Yamamoto K, Yoshimoto T, Takasu A, Ikeya T, Omata F, Fukuda K, Kaise M, Nagata N.Gastrointest Endosc. 97(1):89-99,2023
  25. Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national surveyNakase H, Wagatsuma K, Nojima M, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Takeuchi K, Tamura S, Kinjo F, Ueno N, Naganuma M, Watanabe K, Moroi R, Nishimata N, Motoya S, Kurahara K, Takahashi S, Maemoto A, Sakuraba H, Saruta M, Tominaga K, Hisabe T, Tanaka H, Terai S, Hiraoka S, Takedomi H, Narimatsu K, Endo K, Nakamura M, Hisamatsu T.J Gastroenterol. 58(3):205-216,2023
  26. A combination of hepatic encephalopathy and body mass index was associated with the point of no return for improving liver functional reserve after sofosbuvir/velpatasvir treatment in patients with hepatitis C virus-related decompensated cirrhosisSano T, Amano K, Ide T, Yokoyama K, Noguchi K, Nakamura H, Isoda H, Ohno M, Shirachi M, Morita Y, Yano Y, Sumie S, Kawaguchi T, Kuwahara R, Arinaga-Hino T, Takahashi H, Shakado S, Hirai F, Kawaguchi THepatol Res 53(1):26-34,2023
  27. Fine-needle biopsy with 19G needle is effective in combination with endoscopic ultrasound-guided tissue acquisition for genomic profiling of unresectable pancreatic cancer.Ikeda G, Hijioka S, Nagashio Y, Maruki Y, Ohba A, Hisada Y, Yoshinari M, Harai S, Kitamura H, Koga T, Murashima Y, Maehara K, Okada M, Yamashige D, Okamoto K, Hara H, Hagiwara Y, Agarie D, Takasaki T, Takeshita K, Kawasaki Y, Kondo S, Morizane C, Ueno H, Hiraoka N, Yatabe Y, Saito Y, Iwakiri K, Okusaka T.Dig Endosc 35(1):124-133, 2023
  28. High predictive ability of apparent diffusion coefficient value for wall-invasion pattern of advanced gallbladder carcinomaKoga T, Ishida Y, Hamada Y, Takayama Y, Tsuchiya N, Kitaguchi T, Matsumoto K, Kajiwara M, Naito S, Ishii F, Nakashima R, Sasaki T, Hirai F.Abdom Radiol (NY) 48(3):902-912,2023

症例報告

  1. Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease:First Reported Case and a Listerature ReviewIshibashi H, Imakiire S, Goto M, Nomaru R, Shibata M, Matsuoka H, Yasuda H, Yamashima T, Sakisaka H, Tanabe T, Matsuoka S, Kuno N, Abe K, Funakoshi S, Takamatsu Y, Hirai F, Takeshita M.Intern Med. 61(3)：329-334,2022
  2. Observation of the drainage process of the residual lipoma after endoscopic unroofing technique during colonoscopic evaluation of post-procedural hematochezia.Ko YL, Matsuoka H, Nomaru R, Imakiire S, Sakisaka H, Matsuoka S, Kuno N, Abe K, Funakoshi S, Ishida Y, Ishibashi H, Koga K, Saito T, Takeshita M, Hirai F.Clin J Gastroenterol 15(2)：407-412,2022
  3. Resolution of Laryngeal Ulceration with Prednisolone Therapy in a Patient with Crohn's DiseaseKo YL, Matsuoka H, Nomaru R, Imakiire S, Sakisaka H, Matsuoka S, Kuno N, Abe K, Funakoshi S, Ishida Y, Ishibashi H, Miyagi S, Sakata T, Hirai F.Intern Med doi:10.2169/internalmedicine.0422-22. Online ahead of print.
  4. Eosinophilic Granuloma of the Liver Mimicking Metastatic Liver Tumor: A Case ReportUchida Y, Yokoyama K, Higashi T, Kitaguchi T, Fukuda H, Yamauchi R, Tsuchiya N, Fukunaga A, Umeda K, Takata K, Tanaka T, Takeyama Y, Shakado S, Sakisaka S, Hayashi H, Hamada Y, Nabeshima K, Hirai F.Intern Med. 61(10):1511-1517,2022
  5. Multiple focal fatty changes in the liver in patients with porphyria cutanea tarda: A case series and review of the literatureTakata K, Fukunaga A, Nishizawa S, Uchida Y, Fukuyama M, Nagata T, Higashi T, Fukuda H, Yamauchi R, Tanaka T, Yokoyama K, Morihara D, Takeyama Y, Shakado S, Sakisaka S, Hirai F.J Clin Ultrasound. 50(6):832-842,2022
  6. Pseudocirrhosis Due to Desmoplastic Response to Chemotherapy in Breast Cancer Liver MetastasesTakata K, Mogi A, Yamauchi R, Shakado S, Hirai F.Cureus 14(5):e25321,2022
  7. Improvement of vanishing bile duct syndrome with hyperlipidemiaYamauchi R, Takata K, Fukunaga A, Tanaka T, Yokoyama K, Shakado S, Nabeshima K, Yoshimitsu K, Hirai F.Clin J Gastroenterol 15(4):784-790,2022
  8. Operative findings of the migrated stent into the abdominal cavity following endoscopic ultrasound-guided hepaticogastrostomy: Anchoring force of a novel self-expandable metal stent with an anti-migration system (with video).Koga T, Ishida Y, Hirai F.J Hepatobiliary Pancreat Sci 29(8):e79-e80,2022
  9. A novel self assembling peptide hemostatic gel as an option for initial hemostasis in endoscopic sphincterotomy related hemorrhage: a case seriesIshida Y, Tsuchiya N, Koga T, Kitaguchi T, Matsumoto K, Kuno N, Funakoshi S, Ishibashi H, Ashizuka S, Hirai F.Clin J Gastroenterol 15(6):1210-1215,2022
  10. Two Cases of Rapidly Progressive Fatty Liver Disease due to Pancreatic Exocrine Insufficiency without a History of SurgeryTakata K, Nagata T, Matsumoto K, Miyayama T, Shibata K, Fukuda H, Yamauchi R, Fukunaga A, Tanaka T, Yokoyama K, Shakado S, Sakisaka S, Hirai F.Intern Med doi: 10.2169/internalmedicine.0775-22,2023
  11. Familial Primary Biliary Cholangitis With Different Clinical Courses Based on Anti-gp210 Antibody Positivity: A Report of Two CasesNagata T, Takeyama Y, Shakado S, Hirai F, Nimura S.Cureus 27;15(1):e34275,2023
  12. 内視鏡的胆道ドレナージが有効であった免疫チェックポイント阻害薬関連硬化性胆管炎の一例廣田悠治、福永篤志、高田和英、東　具隆、青山　崇、温　麟太郎、林　博之、松元慶亮、永田貴大、姫野修一、北口恭規、山内　涼、福田洋美、梅田かおる、古賀毅彦、土屋直壮、田中　崇、石田祐介、横山圭二、釈迦堂敏、平井郁仁福岡大医紀 49(2)：101-106, 2022

総説

  1. A review on the current status and definitions of activity indices in inflammatory bowel disease: how to use indices for precise evaluation.Kishi M, Hirai F, Takatsu N, Hisabe T, Takada Y, Beppu T, Takeuchi K, Naganuma M, Ohtsuka K, Watanabe K, Matsumoto T, Esaki M, Koganei K, Sugita A, Hata K, Futami K, Ajioka Y, Tanabe H, Iwashita A, Shimizu H, Arai K, Suzuki Y, Hisamatsu T.J Gastroenterol. 57(4)：246-266,2022
  2. Crohn病における小腸粘膜治癒評価の意義　X線の立場から久能宣昭、阿部光市、船越禎広、石橋英樹、平井郁仁胃と腸 57(2)：163-172,2022
  3. 前投薬によるトラブル発生時の対応　キシロカイン、抗コリン薬、鎮静薬、プロポフォールなど船越禎広、山嶋友実、柴田　衛、能丸遼平、今給黎 宗、向坂秀人、久能宣昭、石橋英樹、平井郁仁消化器内視鏡 34(3)：339-344,2022
  4. 小腸バルーン内視鏡とカプセル内視鏡の進歩山嶋友実、平井郁仁、阿部光市日本臨牀 80(3)：420-426,2022
  5. 縦走潰瘍平井郁仁図説「胃と腸」 画像診断用語集2022 57(5)：556,2022
  6. 敷石像、敷石様外観／炎症性ポリポーシス平井郁仁図説「胃と腸」 画像診断用語集2022 57(5)：557,2022
  7. 良性小腸狭窄に対する内視鏡的バルーン拡張術松岡　賢、船越禎広、阿部光市、久能宣昭、平井郁仁消化器内視鏡 34(4)：683-687,2022
  8. 特集：Evidence & Consensusで押さえる IBDの治療薬 最新版 栄養療法芦塚伸也、今給黎 宗、柴田　衛、能丸遼平、山嶋友実、久能宣昭、石橋英樹、船越禎広、平井郁仁月刊 薬事 64(12):56(2484)-61(2489),2022
  9. アドレノメデュリンの消化管運動や炎症への役割芦塚伸也、北村和雄消化器病学サイエンス 6(3):35(167)-40(172),2022
  10. 【小腸疾患-診断・治療の最新動向-】消化管ポリポーシス　von Recklinghausen病石橋英樹、 二村　聡、 平井郁仁日本臨床 80(増)：252-256,2022
  11. 【小腸疾患-診断・治療の最新動向-】治療法　内視鏡治療　バルーン拡張術阿部光市、 平井郁仁日本臨床 80(増)：102-106,2022
  12. Crohn病の診断と治療　最近の動向を含めて平井郁仁、久能宣昭、阿部光市Gastroenterol Endosc 64(7)：1315-1325,2022
  13. 潰瘍性大腸炎の内視鏡診断と鑑別疾患　正確な診断と状況判断に必要な所見を逃さない向坂秀人、久能宣昭、 阿部光市、船越禎広、石橋英樹、平井郁仁消化器内科 4(6)：15-25,2022
  14. 2. 重症Crohn病に対する治療能丸遼平、久能宣昭、平井郁仁外科 84(10)：1022-1028,2022
  15. 各種疾患におけるステロイドの使い方　潰瘍性大腸炎・クローン病芦塚伸也、今給黎 宗、柴田　衛、能丸遼平、山嶋友実、久能宣昭、石橋英樹、船越禎広、平井郁仁臨牀と研究 99(10)：31(1205)-38(1212), 2022
  16. 潰瘍性大腸炎の診断と疾患活動性の評価岸　昌廣、平井郁仁医学と薬学 79(11)：1451-1459,2022
  17. 【胃疾患アトラス　改訂版】隆起を呈する病変　非上皮性隆起病変　腫瘍性非上皮性病変　胃MALTリンパ腫石橋英樹、二村 聡、平井郁仁消化器内視鏡 34(増) ：124-125,2022

著書

  1. AA型アミロイドーシスに伴う微細病変を全消化管に認めた長期罹患のクローン病患者の一例平井郁仁（分担）AAアミロイドーシス診療ファイル 難治性炎症診療のエッセンス 82-86,2022

福岡大学医学部 消化器内科 All Rights Reserved, 2019